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alternatives_fetal_bovine_serum_industrialization_lab_meat [2020/07/01 09:24]
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alternatives_fetal_bovine_serum_industrialization_lab_meat [2020/07/07 08:02] (current)
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 ====== Fully Define and Synthesize Fetal Bovine Serum For Industrialization of Lab Meat ====== ====== Fully Define and Synthesize Fetal Bovine Serum For Industrialization of Lab Meat ======
 +[[regenetive_medicine_anti_aging_immortality|]]
 {{ ::​fsb.png?​direct300|}} {{ ::​fsb.png?​direct300|}}
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 +[[https://​fcs-free.org/​fcs-database|FCS-free Database]]
  
 The industrialization of lab grown meat means we need to fully define and synthesize growth medium. Lab-grown meat so far requires a product called fetal bovine serum. FBS is made from the blood of cow fetuses. If a cow coming for slaughter happens to be pregnant, the cow is slaughtered and bled, and then the fetus is removed from its mother and brought into a blood collection room. The fetus, which remains alive during the following process to ensure blood quality, has a needle inserted into its heart. Its blood is then drained until the fetus dies, a death that usually takes about five minutes. This blood is then refined, and the resulting extract is FBS. Millions of fetuses are slaughtered this way. The industrialization of lab grown meat means we need to fully define and synthesize growth medium. Lab-grown meat so far requires a product called fetal bovine serum. FBS is made from the blood of cow fetuses. If a cow coming for slaughter happens to be pregnant, the cow is slaughtered and bled, and then the fetus is removed from its mother and brought into a blood collection room. The fetus, which remains alive during the following process to ensure blood quality, has a needle inserted into its heart. Its blood is then drained until the fetus dies, a death that usually takes about five minutes. This blood is then refined, and the resulting extract is FBS. Millions of fetuses are slaughtered this way.
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 {{ ::​t--ucc_ireland--irfp-13.png?​direct |Fetal Bovine Serum Composition}} {{ ::​t--ucc_ireland--irfp-13.png?​direct |Fetal Bovine Serum Composition}}
  
 +Amino acids in bovine oviductal and uterine fluids were measured and compared with those in modified simplex optimized medium (KSOM) supplemented with either fetal calf serum or Minimum Essential Medium amino acids in addition to bovine serum albumin, fetal calf serum or polyvinyl alcohol. Concentrations of cysteine, threonine, tryptophan, alanine, aspartate, glycine, glutamate, proline, β-alanine, and citrulline were higher in oviductal fluids than in KSOM-based culture media. Nonessential and essential amino acids were present in ratios of 5:1 and 2:1 in oviductal and uterine fluids, respectively. Concentrations of alanine (3.7 mM), glycine (14.1 mM) and glutamate (5.5 mM) were high in oviductal fluids, comprising 73% of the free amino acid pool. Of the amino acids measured in uterine fluids, alanine (3.1 mM), glycine (12.0 mM), glutamate (4.2 mM), and serine (2.7 mM) were highest in concentration,​ and the first three comprised 43% of the free amino acid pool. In conclusion, amino acid concentrations in the bovine reproductive tract were substantially higher than those in embryo culture media. Certain amino acids, particularly alanine, glutamate, glycine and taurine, are present in strikingly high concentrations in both oviductal and uterine fluids, suggesting that they might play important roles in early embryo development. The particular pattern of amino acid concentrations may be an important factor to be considered for the improvement of embryo culture media.
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 +<iframe width="​560"​ height="​315"​ src="​https://​www.youtube.com/​embed/​JgFE74NP6aM"​ frameborder="​0"​ allow="​accelerometer;​ autoplay; encrypted-media;​ gyroscope; picture-in-picture"​ allowfullscreen></​iframe>​
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 +[[https://​www.labome.com/​method/​Fetal-Bovine-Serum.html|Fetal Bovine Serum]] \\
 +[[https://​www.frontiersin.org/​articles/​10.3389/​fcell.2016.00115/​full|Making the Switch: Alternatives to Fetal Bovine Serum for Adipose-Derived Stromal Cell Expansion]] \\
alternatives_fetal_bovine_serum_industrialization_lab_meat.1593595454.txt.gz · Last modified: 2020/07/01 09:24 by admin