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regenetive_medicine_anti_aging_immortality [2020/07/13 13:12]
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regenetive_medicine_anti_aging_immortality [2020/07/13 13:48] (current)
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 A recent study, [[https://​ganino.com/​files/​2020.05.07.082917v1.full.pdf|Reversing age: dual species measurement of epigenetic age with a single clock]], the results are significant enough to prompt further interest. A recent study, [[https://​ganino.com/​files/​2020.05.07.082917v1.full.pdf|Reversing age: dual species measurement of epigenetic age with a single clock]], the results are significant enough to prompt further interest.
  
-College labs in their search for a cash cow pill prompted them to dissect blood, but they were soon disappointed as the complexity of the human body cannot be treated in a pill. Interested parties put resources into isolating a single protein but that possibility is long gone and much of the interest with it. While, one protein cannot make it rain perhaps one protein might still be useful for some pathology. Reluctantly,​ we are led into the labyrinth of factors. What are the factors? What is the formula? And will the results be any better than parabiosis? In a recent paper by Irina & Michael Conboy known as "the Conboys"​. [[https://​newatlas.com/​medical/​diluted-blood-plasma-reverse-aging-in-mice/​|Diluted blood plasma found to reverse ageing in mice]] suggest by replacing the plasma of mice with a "​neutral"​ mixture they achieved the same or better tissue rejuvenating results as parabiosis. They did not add young blood factors, instead they removed some blood and injected saline/​albumin neutral replacement to achieve the same results. Mystery deepens, some say albumin is not a neutral substitute. According to the Conboys, 1. the increase in ageing factors are due to the deficient performance of organs in an ageing person, in a young person the organs maintain the proteome, answer to the parabiosis question of organs vs. blood. 2. Ageing factors have a dominant effect when compared to youthful factors to such a degree that extracting ageing factors is enough to slow ageing even without adding youthful factors. Dilution of ageing factors meaning there are less ageing factors total in blood. They report that injecting young blood into an old mouse is not beneficial, but injecting old blood into a young mouse is devastating to the young mouse. It has also been stated previously that heating the blood cancelled its rejuvenating factors, discrepancy?​ We know that heat destroys both cells and proteins. I think adding ​factors is still effective and in the mentality.+College labs in their search for a cash cow pill prompted them to dissect blood, but they were soon disappointed as the complexity of the human body cannot be treated in a pill. Interested parties put resources into isolating a single protein but that possibility is long gone and much of the interest with it. While, one protein cannot make it rain perhaps one protein might still be useful for some pathology. Reluctantly,​ we are led into the labyrinth of factors. What are the factors? What is the formula? And will the results be any better than parabiosis? In a recent paper by Irina & Michael Conboy known as "the Conboys"​. [[https://​newatlas.com/​medical/​diluted-blood-plasma-reverse-aging-in-mice/​|Diluted blood plasma found to reverse ageing in mice]] suggest by replacing the plasma of mice with a "​neutral"​ mixture they achieved the same or better tissue rejuvenating results as parabiosis. They did not add young blood factors, instead they removed some blood and injected saline/​albumin neutral replacement to achieve the same results. Mystery deepens, some say albumin is not a neutral substitute. According to the Conboys, 1. the increase in ageing factors are due to the deficient performance of organs in an ageing person, in a young person the organs maintain the proteome, answer to the parabiosis question of organs vs. blood. 2. Ageing factors have a dominant effect when compared to youthful factors to such a degree that extracting ageing factors is enough to slow ageing even without adding youthful factors. Dilution of ageing factors meaning there are less ageing factors total in blood. They report that injecting young blood into an old mouse is not beneficial, but injecting old blood into a young mouse is devastating to the young mouse. It has also been stated previously that heating the blood cancelled its rejuvenating factors, discrepancy?​ We know that heat destroys both cells and proteins. I do not think the body is producing extra bits in blood for no reason, ​factors is still in the mentality, however they make the point that effective serum in vitro might be the ideal media in vivo and exceeding performance of insitu plasma is possible and the therapy a simple dilution
  
 The last implications the Conboys put forward is speculative,​ that maybe there are no factors at all and that the benefits come from an interruption in intercellular communication,​ perhaps if the cell is not reacting to a condition then it better uses time to do some housekeeping or its homeostasis is subjective to signals from the external environment rather than its actual state. The last implications the Conboys put forward is speculative,​ that maybe there are no factors at all and that the benefits come from an interruption in intercellular communication,​ perhaps if the cell is not reacting to a condition then it better uses time to do some housekeeping or its homeostasis is subjective to signals from the external environment rather than its actual state.
regenetive_medicine_anti_aging_immortality.txt ยท Last modified: 2020/07/13 13:48 by admin